Goals of the ASPIS cluster
Our shared aim is a sustainable, animal-free and reliable approach to chemical risk assessment for the years ahead.
Three projects, one ambition
ASPIS cluster is a joint collaboration of the H2020 funded projects ONTOX, PrecisionTOX and RISKHunt3R. Together they represent Europe’s €60M effort towards the sustainable, animal-free and reliable chemical risk assessment of tomorrow.
Replacing animal testing with human-relevant science
A central goal of the cluster is to develop test strategies based on human cells, tissue models and computational tools. These approaches aim to predict how chemicals behave in the body with greater relevance to people.
- New in vitro models that mimic human biology
- Integrated testing strategies that reduce animal use
- Validated methods ready for regulatory uptake
Roadmap of key objectives
The cluster follows a staged path from method development to practical adoption.
Method development
Projects design and refine new testing approaches, building on existing knowledge and emerging technologies.
Integration and data sharing
Results are combined into shared databases and modelling frameworks, enabling cross-project analysis.
Validation and uptake
Promising methods are validated and prepared for use by regulators, industry and risk assessors.
Gallery of our work
Snapshots from laboratories, data work and collaborative meetings across the cluster.
Why these goals matter
Reliable chemical risk assessment protects people and the environment while respecting animal welfare.
Sustainability
Faster, scalable methods reduce the resources needed for safety evaluations and support a greener research system.
Reliability
Transparent, validated approaches give regulators and industry confidence in the decisions that depend on them.
Join us in shaping safer chemistry
Learn how the ASPIS cluster can support your work on chemical safety and animal-free assessment.
Contact ASPIS