ASPIS Cluster meeting 2022
The ASPIS cluster brings together the ONTOX, PrecisionTOX and RISKHunt3R projects to align scientific methods, data sharing and outcomes for animal-free chemical risk assessment.

Why the cluster met in 2022
The 2022 cluster meeting gave the partners of ONTOX, PrecisionTOX and RISKHunt3R a shared forum to compare progress, confirm priorities and identify where their work overlaps. Each project brings a different strand of expertise, from new approach methodologies to exposure modelling and mechanistic toxicology.
The discussions focused on how these strands can be combined into a coherent framework that regulators and industry can trust for chemical safety decisions.
- Review of ongoing experimental and computational work
- Alignment of data formats and common vocabularies
- Planning of joint outputs for the wider scientific community
Key themes of the meeting
Three areas shaped the exchanges between partners.

Next generation test systems
Partners reviewed advanced in vitro models and their readiness for use in regulatory risk assessment, with attention to reproducibility and biological relevance.

Shared data and knowledge bases
The group examined how structured data, ontologies and open tools can make evidence easier to find, compare and reuse across the three projects.
Programme of the meeting
The meeting followed a structured agenda designed to move from results to joint action.
Project progress updates
Each project presented its main results, open questions and planned deliverables for the coming period.
Cross-project working groups
Partners formed small groups to address shared topics such as data harmonisation, validation strategies and communication.
Planning and next steps
The closing session agreed on milestones, responsibilities and the format of joint publications and workshops.

Working together beyond the meeting
The value of the cluster lies in the connections formed between teams. The meeting reinforced a practice of regular exchange, so that findings from one project can inform the design of another while they are still in progress.
Partners agreed to keep this momentum through shared documentation and joint reporting on the cluster's common objectives.
Frequently asked questions
ASPIS is a joint collaboration of the H2020 funded projects ONTOX, PrecisionTOX and RISKHunt3R, working towards sustainable, animal-free and reliable chemical risk assessment.
The meeting brought together researchers and coordinators from the three participating projects to review progress and plan joint activities.
You can read about our objectives on the goals page or reach out through the contact page for general enquiries.
Stay informed about the cluster
Follow the progress of ONTOX, PrecisionTOX and RISKHunt3R as the cluster moves towards its common goals.
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